ADHD and MDD genetic risk scores were associated with a higher risk of experiencing each type of childhood abuse, while neuroticism, schizophrenia, BPD, and ASD genetic scores were associated with a higher risk of experiencing physical/emotional abuse and physical assault, but not sexual abuse. Using polygenic risk scores for six psychiatric disorders-attention-deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder (BPD), major depressive disorder (MDD), neuroticism, and schizophrenia-we tested whether genetic risk for mental illness was associated with increased risk of experiencing three types of childhood abuse: physical/emotional abuse, physical assault, and sexual abuse, in a cohort of white non-Hispanic women ( n = 11,315). Yet, the hypothesis that individuals who have experienced childhood abuse may carry genetic loading for mental illness has never been tested with genetic data. Twin studies suggest that inherited genetic risk for mental illness may account for some of these associations. People who experience childhood abuse are at increased risk of mental illness.
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Her portrayal of Katharine Hepburn in Martin Scorsese's The Aviator (2004) won her the Academy Award for Best Supporting Actress. She came to international attention as Elizabeth I in the drama film Elizabeth (1998), for which she won the Golden Globe and BAFTA Award for Best Actress, and received her first of seven Academy Award nominations. Blanchett is the recipient of numerous accolades, including two Academy Awards, three British Academy Film Awards, three Screen Actors Guild Awards, and three Golden Globe Awards.Īfter graduating from the National Institute of Dramatic Art, Blanchett began her acting career on the Australian stage, taking on roles in Electra in 1992 and Hamlet in 1994. Regarded as one of the finest actresses of her generation, she is known for her versatile work across independent films, blockbusters, and the stage. Catherine Elise Blanchett AC ( / ˈ b l æ n tʃ ə t/ born ) is an Australian actor and producer. 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